By E.Z. Fisman, A. Tenenbaum, J.S. Borer
The superiority of weight problems, metabolic syndrome and diabetes - 3 hyperlinks of an identical >atherothrombotic chain' - has reached pandemic proportions around the globe. hence, our civilization is at warfare opposed to a threatening enemy: cardio-diabetes. a number of self sufficient physiological tactics underlie the clustering of cardio-diabetes, together with principal weight problems, insulin resistance, dyslipidemia, irritation, impaired glucose tolerance, and high blood pressure. Early detection is of overwhelming significance for public health and wellbeing. The advanced and intimate courting among heart problems and diabetes from uncomplicated technology to medical and healing matters is mentioned during this impressive booklet. starting with molecular, biochemical, inflammatory and mobile features, this e-book keeps with histological and pathophysiological matters, info specific difficulties in particular metabolic and scientific settings, and eventually analyzes a number of elements of medical pharmacology concentrating on the optimum administration of mixed dyslipidemia and non-insulin antidiabetic remedy in cardiac diabetic sufferers. This ebook could be a achieve in wisdom for each heart specialist, diabetologist, professional in inner medication, nutritionalist, common medical professional and clinical scholar.
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Additional info for Cardiovascular Diabetology: Clinical, Metabolic and Inflammatory Facets (Advances in Cardiology)
From Endothelial Dysfunction to Acute Ischemic Syndrome Atherosclerosis has been considered a disease of ‘four concepts’. In a substudy of 5,209 patients from the Framingham Study followed for 10 years, it was seen that those patients with peripheral vascular disease had more probabilities of having an acute myocardial infarction (AMI) or a stroke, while those who had had an AMI had more possibilities of having a stroke or peripheral vascular disease. Also those who had suffered a stroke had more chances of having an AMI or peripheral vascular disease.
Besides, it has been noticed that the presence of diabetes abolishes differences in mortality between genders by enhancing it in women, though it is not possible to rule out an impaired glycemic control with greater levels of glycosylated hemoglobin A1c or a diminished compliance with treatment, conditions frequently seen in women . Studies in animal models have always shown that endothelial dysfunction is present in diabetic individuals though in humans dissimilar responses have been observed .
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