By B.G.J. Knols, C. Louis
Modern study on genetic keep an eye on of disease-transmitting bugs is familiar with types of scientists: those who paintings within the laboratory and people referred to as ‘field people’. over the past decade, either teams appear to have constructed differing learn priorities, handle essentially varied facets in the total self-discipline of infectious-disease keep an eye on, and worse, have built a systematic ‘language’ that's not understood by way of the ‘other’ social gathering. This hole widens each day, among the North and the South, among ecologists and molecular biologists, geneticists and behaviourists, and so on. the necessity to increase a standard learn schedule that bridges this hole has been pointed out as a best precedence by means of all events concerned. in basic terms then shall the target of constructing applicable genetic-control options for vectors of affliction turn into fact. This ebook is the mirrored image of a workshop, held in Nairobi (Kenya) in July 2004. It introduced jointly an outstanding illustration of either molecular and ecological learn and, for the 1st time, incorporated an important variety of researchers from disease-endemic international locations.
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Extra resources for Bridging Laboratory and Field Research for Genetic Control of Disease Vectors (Wageningen UR Frontis Series)
Genetic-control trials have delivered dramatic successes through eradication of target pests, such as the eradication of Glossina austeni from the island of Zanzibar by 1997. With regard to the application of GM approaches for disease-vector control, further containment (in terms of selecting isolated populations) is needed, to overcome potential adverse effects of the introduction of GM insects. The choice for physical islands, far from mainland populations, seems the best option in that regard 25 Chapter 2 Beyond (1) geographic isolation, there are several more key factors affecting the selection of a field site, such as (2) occurrence in a narrow geographic range and (3) appropriately sized area (small enough to be manageable, large enough to be convincing); presence of (4) panmictic populations of (5) one vector species (although another closely related non-transmitting species may be useful as a ‘control’); the target species occurs in relatively (6) low density and can be suppressed with existing vector control tools, and (7) disease transmission, in order to measure a public-health impact of the intervention.
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