By Jean-Pierre Bourguignon, Jean-Claude Carel, Yves Christen
This quantity presents the reader with a pathophysiological standpoint at the position of CNS in puberty and early life, ranging from genetic/molecular facets, dealing with structural/imaging adjustments and resulting in physical/behavioral features. for that reason, popular investigators serious about either animal and human examine shared fresh info in addition to total appraisal of proper questions round CNS regulate of puberty and formative years. without doubt that this quantity will motivate these occupied with both medical learn or medical perform or either within the interesting box of puberty and adolescence.
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Additional info for Brain Crosstalk in Puberty and Adolescence
That is, prepubertal gonadectomy of male rats eliminated the sex difference in the number of BrdU-labeled cells in the SDN, reducing the number of pubertally added cells in males to the number observed in females. In contrast, prepubertal ovariectomy did not affect the number of BrdU-labeled cells added to the female SDN. Thus, ovarian hormones during puberty (or just before) feminize the AVPV but do not appear to actively feminize the SDN at this time. And, conversely, testicular hormones further masculinize the SDN during puberty but do not appear to actively masculinize the AVPV.
In: Pfaff DW, Arnold AP, Etgen AM, Fahrbach SE, Rubin RT (eds) Hormones, brain and behavior. Elsevier, San Diego, pp 385–423 Wiegand SJ, Terasawa E (1982) Discrete lesions reveal functional heterogeneity of suprachiasmatic structures in regulation of gonadotropin secretion in the female rat. M. Burke and J. Bakker Abstract The present study is the first to demonstrate that sex differences in hypothalamic activation upon smelling the chemo-signal androstadienone are not acquired during sexual maturation, under the influence of gonadal hormones during puberty, but might be considered hard-wired responses, which already can be observed in prepubertal children.
References Ahmed EI, Zehr JL, Schulz KM, Lorenz BH, DonCarlos LL, Sisk CL (2008) Pubertal hormones modulate the addition of new cells to sexually dimorphic brain regions. Nat Neurosci 11:995–997 Arai Y, Murakami S, Nishizuka M (1994) Androgen enhances neuronal degeneration in the developing preoptic area: apoptosis in the anteroventral periventricular nucleus (AVPvNPOA). Horm Behav 28:313–319 Arai Y, Sekine Y, Murakami S (1996) Estrogen and apoptosis in the developing sexually dimorphic preoptic area in female rats.